Oprah Winfrey

Imagine pitting Oprah against any other talk show host in the 'Greatest Talk Show Hosts of All Time' league. It’s like bringing a library to a book fight. The woman practically invented emotional catharsis for daytime TV viewers and turned book recommendations into a competitive sport. Fans are either tearing up thanking her for enlightening their lives or furiously debating why their favorite book didn't make her list. Seriously, choosing between Oprah and anyone else is like trying to pick between breathing air and, well, not.