Jerry Seinfeld & George Costanza (Seinfeld)

Picture this: Jerry Seinfeld and George Costanza—the quintessential neurotic duo. These two aren't just friends; they're a full-on cultural cyclone that swept up the '90s and never really put it back down. Ever tried explaining their appeal? It's like trying to describe why you laugh at a grapefruit—it's absurd, it's pointless, but man, is it entertaining. They've turned awkward pauses and bizarre predicaments into an art form. If there's a 'Greatest Iconic TV Duos' list worth its salt, these guys top it. Not just for laughs, but for making the mundane unmissably hilarious.